Toward local arterial input functions in dynamic contrast-enhanced MRI
نویسندگان
چکیده
منابع مشابه
Toward local arterial input functions in dynamic contrast-enhanced MRI.
PURPOSE To present a method for estimating the local arterial input function (AIF) within a dynamic contrast-enhanced MRI scan, based on the alternating minimization with model (AMM) method. MATERIALS AND METHODS This method clusters a subset of data into representative curves, which are then input to the AMM algorithm to return a parameterized AIF and pharmacokinetic parameters. Computer sim...
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Compared to gold-standard measurements of cerebral perfusion with positron emission tomography using H(2)[(15)O] tracers, measurements with dynamic susceptibility contrast MR are more accessible, less expensive, and less invasive. However, existing methods for analyzing and interpreting data from dynamic susceptibility contrast MR have characteristic disadvantages that include sensitivity to in...
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Introduction The accuracy in pharmacokinetic parameters derived from Dynamic Contrast-Enhanced MRI (DCE-MRI) depends strongly on the quality of the arterial input function (AIF). The AIF is challenging to measure accurately for several reasons. For example, T1 needs to be determined with a temporal resolution of about one second and with a spatial resolution high enough to resolve the artery wh...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2010
ISSN: 1053-1807
DOI: 10.1002/jmri.22339